Academic Radiology
Volume 13, Issue 6 , Pages 752-758 , June 2006

Quantitative Analysis of Brain Asymmetry by Using the Divergence Measure: Normal-Pathological Brain Discrimination

  • Ihar Volkau, PhD

      Affiliations

    • Agency for Science, Technology and Research (A*STAR), Biomedical Imaging Lab, 30 Blopolis Road, 07-01, Matrix, Singapore, 138671, Singapore
    • Corresponding Author InformationAddress correspondence to: I.V.
    • ,
  • Bhanu Prakash, KN, PhD

      Affiliations

    • Agency for Science, Technology and Research (A*STAR), Biomedical Imaging Lab, 30 Blopolis Road, 07-01, Matrix, Singapore, 138671, Singapore
    • ,
  • Anand Ananthasubramaniam, ME

      Affiliations

    • Agency for Science, Technology and Research (A*STAR), Biomedical Imaging Lab, 30 Blopolis Road, 07-01, Matrix, Singapore, 138671, Singapore
    • ,
  • Varsha Gupta, PhD

      Affiliations

    • Agency for Science, Technology and Research (A*STAR), Biomedical Imaging Lab, 30 Blopolis Road, 07-01, Matrix, Singapore, 138671, Singapore
    • ,
  • Aamer Aziz, PhD, MD

      Affiliations

    • Regional Imaging, PO Box 5576, Wagga Wagga NSW, Australia, 2650.
    • ,
  • Wieslaw L. Nowinski, PhD, DSc

      Affiliations

    • Agency for Science, Technology and Research (A*STAR), Biomedical Imaging Lab, 30 Blopolis Road, 07-01, Matrix, Singapore, 138671, Singapore

Received 20 June 2005 ,Accepted 17 January 2006.

References 

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  3. Thirion J-P , Prima S , Subsol G , Roberts N . Statistical analysis of normal and abnormal dyssymmetry in volumetric medical images . Med Image Anal . 2000;4:111–121
  4. Joshi S , Lorenzen P , Gerig G , Bullitt E . Structural and radiometric asymmetry in brain images . Med Image Anal . 2003;7:155–170
  5. Hopkins WD , Rilling JK . A comparative MRI study of the relationship between neuroanatomical asymmetry and interhemispheric connectivity in primates (implication for the evolution of functional asymmetries) . Behav Neurosci . 2000;114(4):739–748
  6. Jeffreys H . An invariant form for the prior probability in estimation problems . Proc R Soc Lond Ser A . 1946;186:453–461
  7. Hu Q , Nowinski WL . A rapid algorithm for robust and automatic extraction of the midsagittal plane of the human cerebrum from neuroimages based on local symmetry and outlier removal . NeuroImage . 2003;20:2154–2166
  8. Wilk MB , Gnanadesikan R . Probability plotting methods for the analysis of data . Biometrika . 1968;55:1–17
  9. Lilliefors H . On the Kolmogorov-Smirnov test for normality with mean and variance unknown . J Am Stat Assoc . 1967;62:399–402
  10. Shapiro SS , Wilk MB . An analysis of variance test for normality (complete samples) . Biometrika . 1965;52:591–611
  11. Duda RO , Hart PE . Pattern Classification and Scene Analysis . New York: John Wiley; 1973;
  12. Hanley JA , McNeil BJ . The meaning and use of the area under a receiver operating characteristic (ROC) curve . Radiology . 1982;143:29–36
  13. Zweig MH , Campbell G . Receiver-operating characteristic (ROC) plots (A fundamental evaluation tool in clinical medicine) . Clin Chem . 1993;39:561–577
  14. Volkau I, Aziz A, Bhanu Prakash KN, Anand A, Teistler M, Nowinski W. Visualization of brain asymmetries caused by abnormality. Program 91st Radiological Society of North America Scientific Assembly and Annual Meeting RSNA 2005, Chicago, Illinois, USA, 27 November–2 December 2005:857.

PII: S1076-6332(06)00051-1

doi: 10.1016/j.acra.2006.01.043

Academic Radiology
Volume 13, Issue 6 , Pages 752-758 , June 2006

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