Academic Radiology
Volume 15, Issue 3 , Pages 334-341 , March 2008

Reproducibility of Tumor Volume Measurement at MicroCT Colonography in Living Mice

  • Benjamin Y. Durkee

      Affiliations

    • Department of Medical Physics, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • ,
  • Sarah R. Mudd

      Affiliations

    • Department of Pharmacy, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • ,
  • Calista N. Roen

      Affiliations

    • Department of Radiology, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • ,
  • Linda Clipson

      Affiliations

    • Department of Oncology, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • ,
  • Michael A. Newton

      Affiliations

    • Department of Statistics, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • Department of Biostatistics and Medical Informatics, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • Paul P. Carbone Comprehensive Cancer Center, 1400 University Avenue, University of Wisconsin, Madison, WI 53706.
    • ,
  • Jamey P. Weichert

      Affiliations

    • Department of Medical Physics, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • Department of Radiology, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • Paul P. Carbone Comprehensive Cancer Center, 1400 University Avenue, University of Wisconsin, Madison, WI 53706.
    • ,
  • Perry J. Pickhardt, MD

      Affiliations

    • Department of Radiology, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • ,
  • Richard B. Halberg

      Affiliations

    • Department of Oncology, 1400 University Avenue, University of Wisconsin, Madison, WI 53706
    • Corresponding Author InformationAddress correspondence to: R.B.H.

Received 20 June 2007 ,Accepted 4 October 2007.

References 

  1. American Cancer Society. Cancer facts & figures 2007. Atlanta, Ga: American Cancer Society; 2007;
  2. Pickhardt PJ, Choi JR, Hwang I, et al. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. New Engl J Med. 2003;349:2191–2200
  3. Pickhardt PJ, Halberg RB, Taylor AJ, et al. Microcomputed tomography colonography for polyp detection in an in vivo mouse tumor model. Proc Natl Acad Sci U S A. 2005;102:3419–3422
  4. Ware JH. Linear models for the analysis of longitudinal studies. Am Stat. 1985;39:95–101
  5. Yeshwant SC, Summers RM, Yao J, et al. Polyps: linear and volumetric measurement at CT colonography. Radiology. 2006;241:802–811
  6. Su LK, Kinzler KW, Vogelstein B, et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science. 1992;256:668–670
  7. Quon A, Napel S, Beaulieu CF, et al. “Flying through” and “flying around” a PET/CT scan: pilot study and development of 3D integrated 18F-FDG PET/CT for virtual bronchoscopy and colonoscopy. J Nucl Med. 2006;47:1081–1087
  8. Magnotta VA, Heckel D, Andreasen NC, et al. Measurement of brain structures with artificial neural networks: two- and three-dimensional applications. Radiology. 1999;211:781–790
  9. Heidelberger C, Ansfield FJ. Experimental and clinical use of fluorinated pyrimidines in cancer chemotherapy. Cancer Res. 1963;23:1226–1243

1 Supported by funds to Jamey Weichert from the University of Wisconsin Comprehensive Cancer Center, a R37 grant CA63677 to William F. Dove from the National Cancer Institute, and a NCDDG grant U19 CA113297-03 to Ben Shen from the National Cancer Institute.

PII: S1076-6332(07)00570-3

doi: 10.1016/j.acra.2007.10.005

Academic Radiology
Volume 15, Issue 3 , Pages 334-341 , March 2008

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