Academic Radiology
Volume 16, Issue 10 , Pages 1201-1207 , October 2009

Hemodynamics and Rupture of Terminal Cerebral Aneurysms

  • Marcelo Castro, PhD

      Affiliations

    • Center for Computational Fluid Dynamics, Department of Computational and Data Sciences, George Mason University, 4400 University Drive, MSN 6A2, Fairfax, VA 22030
    • Corresponding Author InformationAddress correspondence to: M.C.
    • ,
  • Christopher Putman, MD, PhD

      Affiliations

    • Interventional Neuroradiology, Inova Fairfax Hospital, Falls Church, VA
    • ,
  • Alessandro Radaelli, PhD

      Affiliations

    • Center for Computational Imaging & Simulation, Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain
    • ,
  • Alejandro Frangi, PhD

      Affiliations

    • Center for Computational Imaging & Simulation, Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain
    • ,
  • Juan Cebral, PhD

      Affiliations

    • Center for Computational Fluid Dynamics, Department of Computational and Data Sciences, George Mason University, 4400 University Drive, MSN 6A2, Fairfax, VA 22030

Received 20 January 2009 ,Accepted 31 March 2009.

References 

  1. Hashimoto N, Handa H, Nagata I, et al. Experimentally induced cerebral aneurysms in rats: part V, relation of hemodynamics in the circle of Willis to formation of aneurysms. Surg Neurol. 1980;13:41–45
  2. Nakatani H, Hashimoto N, Kang Y, et al. Cerebral blood flow patterns at major vessel bifurcations and aneurysms in rats. J Neurosurg. 1991;74:258–262
  3. Gonzalez CF, Cho YI, Ortega HV, et al. Intracranial aneurysms: flow analysis of their origin and progression. AJNR Am J Neuroradiol. 1992;13:181–188
  4. Gobin YP, Counord JL, Flaud P, et al. In vitro study of haemodynamics in a giant saccular aneurysm model: influence of flow dynamics in the parent vessel and effects of coil embolization. Neuroradiology. 1994;36:530–536
  5. Burleson AC, Strother CM, Turitto VT, et al. Computer modeling of intracranial saccular and lateral aneurysms for the study of their hemodynamics. Neurosurgery. 1995;37:774–784
  6. Tenjin H, Asakura F, Nakahara H, et al. Evaluation of intraaneurysmal blood velocity by time-density curve analysis and digital subtraction angiography. AJNR Am J Neuroradiol. 1998;19:1303–1307
  7. Ujie H, Tachibana H, Hiramatsu O, et al. Effects of size and shape (aspect ratio) on the hemodynamics of saccular aneurysms: a possible index for the surgical treatment of intracranial aneurysms. Neurosurgery. 1999;45:119–130
  8. Tateshima S, Murayama Y, Villablanca JP, et al. Intraaneurysmal flow dynamics study featuring an acrylic aneurysm model manufactured using computerized tomography angiogram as a mold. J Neurosurg. 2001;95:1020–1027
  9. Saton T, Onoda K, Tsuchimoto S, et al. Visualization of intraaneurysmal flow patterns with transluminal flow images of 3D MR angiograms in conjunction with aneurysmal configurations. Am J Neuroradiol. 2003;24:1436–1445
  10. Liou TM, Liou SN. A review of in vitro studies of hemodynamic characteristics in terminal and lateral aneurysm models. Proc. Natl. Sci. Counc. ROC(B). 1999;23:133–148
  11. Cebral JR, Castro MA, Appanaboyina S, et al. Efficient pipeline for image-based patient-specific analysis of cerebral aneurysm hemodynamics: technique and sensitivity. IEEE Trans Med Imaging. 2005;24:457–467
  12. Cebral JR, Castro MA, Burguess JE, et al. Characterization of cerebral aneurysm for assessing risk of rupture using patient-specific computational hemodynamics models. AJNR Am J Neuroradiol. 2005;26:2550–2559
  13. Castro MA, Putman CM, Sheridan MJ, et al. Hemodynamic patterns of anterior communicating artery aneurysms: a possible association with rupture. AJNR Am J Neuroradiol. 2009;30:297–302
  14. Yim PJ, Vasbinder GB, Ho VB, et al. A deformable isosurface and vascular applications. SPIE Med Imaging. 2002;4684:1390–1397
  15. Castro MA, Putman CM, Cebral JR, et al. Computational fluid dynamics modeling of intracranial aneurysms: effects of parent artery segmentation on intra-aneurysmal hemodynamics. AJNR Am J Neuroradiol. 2006;27:1703–1709
  16. Taubin G. Signal processing approach to fair surface design. Comp Graphics. 1995;351–358
  17. Cebral JR, Löhner R. From medical images to anatomically accurate finite element grids. Int J Numerical Meth Engineer. 2001;51:985–1008
  18. Löhner R. Automatic unstructured grid generators. Finite Elements Anal Design. 1997;25:111–134
  19. Löhner R. Communications in numerical methods in engineering. 1996;12:683–702
  20. Löhner R. Regridding surface triangulations. J Comp Phys. 1996;126:1–10
  21. Mazumdar J. Biofluid mechanics. Singapore: World Scientific; 1992;
  22. Cebral JR, et al. Flow-area relationship in internal carotid and vertebral arteries. Physiol Meas. 2008;29:585–594
  23. Womersley JR. Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known. J Physiol. 1955;127:553–563
  24. Taylor CA, Hughes TJR, Zarins CK, et al. Finite element modeling of blood flow in arteries. Comp Meth Appl Mechand Engineer. 1998;158:155–196
  25. Stehbens WE. Intracranial arterial aneurysms in pathology of the cerebral blood vessels. 1972;351–470
  26. Weir B. Unruptured intracranial aneurysms: a review. J Neurosurg. 2002;96:3–42
  27. Foutrakis GN, Yonas H, Scablassi R, et al. Saccular aneurysm formation in curved and bifurcation arteries. AJNR Am J Neuroradiol. 1999;20:1309–1317
  28. Tomasello F, D'Avella D, Salpietro FM, et al. Asymptomatic aneurysms. Literature meta-analysis and indications for treatment. J Neurosurg Sci. 1998;42:47–51
  29. Winn HR, Jane JA, Taylor J, et al. Prevalence of asymptomatic incidental aneurysms: review of 4568 arteriograms. J Neurosurg. 2002;96:43–49
  30. Linn FHH, Rinkel GJE, Algra A, et al. Incidence of subarachnoid hemorrhage: role of region, year, and rate of computed tomography: a meta-analysis. Stroke. 1996;27:625–629
  31. Kaminogo M, Yonekura M, Shibata S, et al. Incidence and outcome of multiple intracranial aneurysms in a defined population. Stroke. 2003;34:16–21
  32. Kim C, Cervós-Navarro J, Pätzold C, et al. In vivo study of flow pattern at human carotid bifurcation with regard to aneurysm development. Acta Neurochir (Wien). 1992;115:112–117
  33. Kassell NF, Torner JC. The International Cooperative Study on the Timing of Aneurysm Surgery. Part 1: overall management results. J Neurosurg. 1990;73:18–36
  34. Nishioka H, Torner JC, Graf CJ, et al. Cooperative study of intracranial aneurysms and subarachnoid hemorrhage: a long-term prognostic study. II. Ruptured intracranial aneurysms managed conservatively. Arch Neurol. 1984;41:1142–1146
  35. White PM, Wardlaw JM. Unruptured intracranial aneurysms. J Neuroradiol. 2003;30:336–350
  36. Reneman RS, et al. Wall shear stress—an important determination of endothelial cell function and structure—in arterial system in vivo. J Vasc Res. 2006;43:251–269
  37. Forsberg F, Morvay Z, Rawool NM, et al. Shear rate estimation using a clinical ultrasound scanner. J Ultrasound Med. 2000;19:323–327

 Supported by Philips Medical Systems, American Heart Association.

PII: S1076-6332(09)00257-8

doi: 10.1016/j.acra.2009.03.022

Academic Radiology
Volume 16, Issue 10 , Pages 1201-1207 , October 2009

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