Academic Radiology
Volume 17, Issue 1 , Pages 1-2 , January 2010

EGFR Targeted Fluorescence Imaging in Gliomas

Received 30 October 2009 ,Accepted 30 October 2009.

References 

  1. Hollingworth W, Medina LS, Lenkinski RE, et al. A systematic literature review of magnetic resonance spectroscopy for the characterization of brain tumors. AJNR Am J Neuroradiol. 2006;27:1404–1411
  2. Chawla S, Poptani H, Melhem ER. Anatomic, physiologic and metabolic imaging in neuro-oncology. Cancer Treat Res. 2008;143:3–42
  3. Delikatny EJ, Poptani H. MR techniques for in vivo molecular and cellular imaging. Radiol Clin North Am. 2005;43:205–220
  4. Shah K, Weissleder R. Molecular optical imaging: applications leading to the development of present day therapeutics. NeuroRx. 2005;2:215–225
  5. Kumar S, Richards-Kortum R. Optical molecular imaging agents for cancer diagnostics and therapeutics. Nanomedicine. 2006;1:23–30
  6. Ke S, Wen X, Gurfinkel M, et al. Near-infrared optical imaging of epidermal growth factor receptor in breast cancer xenografts. Cancer Res. 2003;63:7870–7875
  7. Mischel PS, Cloughesy TF. Targeted molecular therapy of GBM. Brain Pathol. 2003;13:52–61
  8. Kim ES, Kies M, Herbst RS. Novel therapeutics for head and neck cancer. Curr Opin Oncol. 2002;14:334–342
  9. Matter A. Tumor angiogenesis as a therapeutic target. Drug Discov Today. 2001;6:1005–1024
  10. Wood JM, Bold G, Buchdunger E, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res. 2000;60:2178–2189
  11. Gibbs-Strauss SL, Samkoe KS, O'Hara JA, et al. Detecting epidermal growth factor receptor tumor activity in vivo during cetuximab therapy in murine gliomas. Acad Radiol. 2010;17:7–17
  12. Asgari S, Rohrborn HJ, Engelhorn T, Stolke D. Intra-operative characterization of gliomas by near-infrared spectroscopy: possible association with prognosis. Acta Neurochirurgica. 2003;145:453–460
  13. Gibbs-Strauss SL, O'Hara JA, Srinivasan S, Hoopes PJ, Hasan T, Pogue BW. Diagnostic detection of diffuse glioma tumors in vivo with molecular fluorescent probe-based transmission spectroscopy. Med Phys. 2009;36:974–983

PII: S1076-6332(09)00597-2

doi: 10.1016/j.acra.2009.10.025

Academic Radiology
Volume 17, Issue 1 , Pages 1-2 , January 2010

Article Tools