Academic Radiology
Volume 17, Issue 4 , Pages 489-495 , April 2010

Collapsibility of Lung Volume by Paired Inspiratory and Expiratory CT Scans: Correlations with Lung Function and Mean Lung Density

  • Tsuneo Yamashiro, MD

      Affiliations

    • Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Boston, MA
    • Department of Radiology, University of the Ryukyus, 207 Uehara, Nishihara-cho, Okinawa 903-0215, Japan
    • Corresponding Author InformationAddress correspondence to: T.Y.
    • ,
  • Shin Matsuoka, MD, PhD

      Affiliations

    • Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Boston, MA
    • Department of Radiology, St. Marianna University School of Medicine, Kawasaki, Japan
    • ,
  • Brian J. Bartholmai, MD

      Affiliations

    • Department of Radiology, Mayo Clinic, Rochester, MN
    • ,
  • Raúl San José Estépar, PhD

      Affiliations

    • Surgical Planning Laboratory, Brigham and Women's Hospital, Boston, MA
    • ,
  • James C. Ross, MS

      Affiliations

    • Surgical Planning Laboratory, Brigham and Women's Hospital, Boston, MA
    • ,
  • Alejandro Diaz, MD

      Affiliations

    • Pulmonary and Critical Care Division, Brigham and Women's Hospital, Boston, MA
    • Pontificia Universidad Catolica de Chile, Santiago, Chile
    • ,
  • Sadayuki Murayama, MD, PhD

      Affiliations

    • Department of Radiology, University of the Ryukyus, 207 Uehara, Nishihara-cho, Okinawa 903-0215, Japan
    • ,
  • Edwin K. Silverman, MD, PhD

      Affiliations

    • Pulmonary and Critical Care Division, Brigham and Women's Hospital, Boston, MA
    • Channing Laboratory, Brigham and Women's Hospital, Boston, MA
    • ,
  • Hiroto Hatabu, MD, PhD

      Affiliations

    • Center for Pulmonary Functional Imaging, Brigham and Women's Hospital, Boston, MA
    • ,
  • George R. Washko, MD

      Affiliations

    • Pulmonary and Critical Care Division, Brigham and Women's Hospital, Boston, MA

Received 6 July 2009 ,Accepted 3 November 2009.

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 This study used data provided by the Lung Tissue Research Consortium (LTRC) supported by the National Heart, Lung and Blood Institute.

 This study is supported by NIH K23HL089353-01A1 and a grant from the Parker B. Francis Foundation.

 Dr. Yamashiro, Dr. Matsuoka, Dr. Bartholmai, Dr. San Jose Estepar, Mr. Ross, Dr. Diaz, Dr. Murayama, Dr. Hatabu, and Dr. Washko have no conflicts of interest to disclose. Dr. Silverman received an honorarium for a talk on chronic obstructive pulmonary disease genetics in 2006, and grant support and consulting fees from GlaxoSmithKline for two studies of chronic obstructive pulmonary disease genetics. Dr. Silverman also received honoraria from Bayer in 2005, and from AstraZeneca in 2007 and 2008.

PII: S1076-6332(09)00629-1

doi: 10.1016/j.acra.2009.11.004

Academic Radiology
Volume 17, Issue 4 , Pages 489-495 , April 2010

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