Academic Radiology
Volume 17, Issue 4 , Pages 456-463 , April 2010

The Role of Parallel Diffusion-Weighted Imaging and Apparent Diffusion Coefficient (ADC) Map Values for Evaluating Breast Lesions: Preliminary Results

  • Guangwei Jin, MD

      Affiliations

    • Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China 100053
    • Department of Radiology, Meitan General Hospital, Beijing, China 100028
    • ,
  • Ningyu An, MD

      Affiliations

    • Department of Radiology, PLA General Hospital, Beijing, China
    • ,
  • Michael A. Jacobs, PhD

      Affiliations

    • The Russell H. Morgan Department of Radiology and Radiological Science and Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD
    • ,
  • Kuncheng Li, MD

      Affiliations

    • Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China 100053
    • Corresponding Author InformationAddress correspondence to: K.L.

Received 26 August 2009 ,Accepted 4 December 2009.

References 

  1. Heywang SH, Fenzl G, Beck R, et al. Use of Gd-DTPA in the nuclear magnetic resonance study of the breast. Rofo. 1986;145:565–571
  2. Kaiser WA, Zeitler E. MR imaging of the breast: fast imaging sequences with and without Gd-DTPA. Preliminary observations. Radiology. 1989;170:681–686
  3. Kuhl CK, Mielcareck P, Klaschik S, et al. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?. Radiology. 1999;211:101–110
  4. Lehman CD, Schnall MD. Imaging in breast cancer: magnetic resonance imaging. Breast Cancer Res. 2005;7:215–219
  5. Bluemke DA, Gatsonis CA, Chen MH, et al. Magnetic resonance imaging of the breast prior to biopsy. JAMA. 2004;292:2735–2742
  6. Choi N, Han BK, Choe YH, et al. Three-phase dynamic breast magnetic resonance imaging with two-way subtraction. J Comput Assist Tomogr. 2005;29:834–841
  7. Le Bihan D, Breton E, Lallemand D, et al. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology. 1986;161:401–407
  8. Barber PA, Hill MD, Eliasziw M, et al. Imaging of the brain in acute ischaemic stroke: comparison of computed tomography and magnetic resonance diffusion-weighted imaging. J Neurol Psychiatry. 2005;76:1528–1533
  9. Chenevert TL, Stegman LD, Taylor JM, et al. Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst. 2000;92:2029–2036
  10. Kucharczyk J, Mintorovitch J, Asgari HS, et al. Diffusion/perfusion MR imaging of acute cerebral ischemia. Magn Reson Med. 1991;19:311–315
  11. Brunberg JA, Chenevert TL, McKeever PE, et al. In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres. AJNR Am J Neuroradiol. 1995;16:361–371
  12. Englander SA, Uluğ AM, Brem R, et al. Diffusion imaging of human breast. NMR Biomed. 1997;10:348–352
  13. Guo Y, Cai YQ, Cai ZL, et al. Differentiation of clinically benign and malignant breast lesions using diffusion-weighted imaging. J Magn Reason Imaging. 2002;16:172–178
  14. Sinha S, Lucas-Quesada FA, Sinha U, et al. In vivo diffusion-weighted MRI of the breast: potential for lesion characterization. J Magn Reson Imaging. 2002;15:693–704
  15. Kinoshita T, Yashiro N, Ihara N, et al. Diffusion-weighted half-Fourier single-shot turbo spin echo imaging in breast tumor: differentiation of invasive ductal carcinoma from fibroadenoma. J Comput Assist Tomogr. 2002;26:1042–1046
  16. Woodhams R, Matsunaga K, Iwabuchi K, et al. Diffusion-weighted imaging of malignant breast tumors: the usefulness of apparent diffusion coefficient (ADC) value and ADC map for the detection of malignant breast tumors and evaluation of cancer extension. J Comput Assist Tomogr. 2005;29:644–649
  17. Park MJ, Cha ES, Kang BJ, et al. The role of diffusion-weighted imaging and the apparent diffusion coefficient (ADC) values for breast tumors. Korean J Radiol. 2007;8:390–396
  18. Kuroki Y, Nas K, Kuroki S, et al. Diffusion-weighted imaging of breast cancer with the sensitivity encoding technique: analysis of the apparent diffusion coefficient value. Magn Reson Med Sci. 2004;3:79–85
  19. Humphries PD, Sebire NJ, Siegel MJ, et al. Tumors in pediatric patients at diffusion-weighted MR imaging: apparent diffusion coefficient and tumor cellularity. Radiology. 2007;245:848–854
  20. Squillaci E, Manenti G, Cova M, et al. Correlation of diffusion-weighted MR imaging with cellularity of renal tumours. Anticancer Res. 2004;24:4175–4179
  21. Manenti G, Di Roma M, Mancino S, et al. Malignant renal neoplasms: correlation between ADC values and cellularity in diffusion weighted magnetic resonance imaging at 3 T. Radiol Med. 2008;113:199–213
  22. Sugahara T, Korogi Y, Kochi M, et al. Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas. J Magn Reson Imaging. 1999;9:53–60
  23. Hatakenaka M, Soeda H, Yabuuchi H, et al. Apparent diffusion coefficients of breast tumors: clinical application. Magn Reson Med Sci. 2008;7:23–29
  24. Ducatman BS, Emery ST, Wang HH. Correlation of histologic grade of breast carcinoma with cytologic features on fine-needle aspiration of the breast. Mod Pathol. 1993;6:539–543
  25. Woodhams R, Matsunaga K, Kan S, et al. ADC mapping of benign and malignant breast tumors. Magn Reson Med Sci. 2005;4:35–42
  26. Le Bihan D, Breton E, Lallemand D, et al. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology. 1988;168:497–505
  27. Morvan D. In vivo measurement of diffusion and pseudo-diffusion in skeletal muscle at rest and after exercise. Magn Reson Imaging. 1995;13:193–199
  28. Thoeny HC, De Keyzer F, Boesch C, et al. Diffusion-weighted imaging of the parotid gland: Influence of the choice of b-values on the apparent diffusion coefficient value. J Magn Reson Imaging. 2004;20:786–790
  29. Wheeler-Kingshott CA, Thomas DL, Lythgoe MF, et al. Burst excitation for quantitative diffusion imaging with multiple b-values. Magn Reson Med. 2000;44:737–745

 This work was supported in part by NIH 1R01CA100184.

PII: S1076-6332(09)00674-6

doi: 10.1016/j.acra.2009.12.004

Academic Radiology
Volume 17, Issue 4 , Pages 456-463 , April 2010

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