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Cover 1
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CO1
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Distribution List Name: 1-CMR Attendees Members and e-mail addresses:
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S1
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Feridex-Labeled Mesenchymal Stem Cells: Cellular Differentiation and MR Assessment in a Canine Myocardial Infarction Model
Attempts to regenerate myocardium after experimentally induced acute myocardial infarction (MI) by cellular myoplasty techniques have recently provided encouraging results []. Transplantation and mobi...
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Jeff W.M. Bulte,
Lisa Kostura,
Alistair Mackay,
Parag V. Karmarkar,
Izlem Izbudak,
Ergin Atalar,
Danielle Fritzges,
E. Rene Rodriguez,
Randy G. Young,
Michelle Marcelino,
Mark F. Pittenger,
Dara L. Kraitchman
et al.
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S2-S6
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Subchronic Toxicity of the Gadolinium Chelates
Differences in safety profile between the four gadolinium chelates approved for clinical use by the Food and Drug Administration (FDA) are known, but have received in general little attention.[] The r...
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Val M. Runge,
Thomas J. Kuehl,
Carney B. Jackson,
Elissa A. Estrada
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S6-S9
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Molecular Imaging of Human Thrombus with Computed Tomography
The formation of thrombus on ruptured atherosclerotic plaques is well recognized as the precursor of myocardial infarction and stroke[]. Although several techniques exist for the detection of lumenal ...
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Patrick M. Winter,
Himanshu P. Shukla,
Shelton D. Caruthers,
Michael J. Scott,
Ralph W. Fuhrhop,
J. David Robertson,
Patrick J. Gaffney,
Samuel A. Wickline,
Gregory M. Lanza
et al.
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S9-S13
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Drug Delivery by Angiographic Contrast Media: Inhibition of Restenosis
Angioplasty without and with stent implantation is an established minimally invasive procedure for treating localized stenosis in a variety of blood vessels. A high acute success rate is reduced by re...
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Ulrich Speck,
Bruno Scheller,
Claudia Abramjuk,
Ulrich Bernhardt
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S14-S17
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Detection Of Liver Metastases From Gastrointestinal Cancer: Comparision Of High Resolution MnDPDP Enhanced MRI And FDG-PET
Liver is the commonest site of distant metastases in gastrointestinal cancer (). Early detection of liver metastases is paramount, especially in colorectal cancer because of improved 2-year survival r...
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Sanjeeva P. Kalva,
Dushyant V. Sahani,
David Ryan,
Alan J. Fischman,
Peter F. Hahn,
Peter Mueller,
Sanjay Saini
et al.
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S17-S20
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Oral manganese for liver and bile imaging
To study the signal intensity of the liver, bile and the bowel content before and after ingestion of a new oral manganese containing contrast medium (CMC-001; CMC Contrast AB, Malmoe, Sweden) at three...
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Henrik S. Thomsen,
Vibeke Loegager,
Henrik Noerrgaard,
Elizaveta Chabanova,
Jakob Moller,
Jesper Sonne
et al.
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S21-S23
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Gadobenate dimeglumine (MultiHance®) in MR imaging of the CNS: studies to assess the benefits of a high relaxivity contrast agent
Today, several gadolinium (Gd)-based MR contrast media are in widespread use for MR imaging of the CNS. Those considered “first generation” agents comprise Magnevist (Gd-DTPA, gadopentetate dimeglumin...
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Marco Essig
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S23-S27
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Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue™ to monitor the effects of different anti-angiogenic therapies
Angiogenesis is a critical step in the progression and metastasis of tumor cells[]. Considerable efforts have been directed to quantitatively detect tumor angiogenesis as well as to monitor the impact...
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A. Broillet,
J. Hantson,
C. Ruegg,
T. Messager,
M. Schneider
et al.
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S28-S33
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Technical and Practical Considerations for Permeability Modeling of Dynamic Contrast Enhanced MRI
Characterization of the microvasculature by kinetic modeling of dynamic contrast enhanced MRI (dCE-MRI) is emerging as a powerful approach to the study of angiogenesis and the monitoring of therapeuti...
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Tim Roberts
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S34-S37
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Optimized Labeling of Hematopoietic Progenitor Cells derived from umbilical cord blood or peripheral blood with iron oxide contrast agents for in vivo depiction with MR imaging at 1.5 Tesla
Human hematopoietic progenitor cells from umbilical cord blood and progenitor cells from peripheral blood have different biological properties. Thus, labeling of these cells with MR contrast agents ha...
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Heike E. Daldrup-Link,
Martina Rudelius,
Guido Piontek,
Marcus Settles,
Hilkea Rosenbrock,
Thomas M. Link,
Ernst J. Rummeny,
Robert A.J. Oostendorp
et al.
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S38-S39
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Glucose Receptor Magnetic Resonance Imaging of Tumors: Experimental Study With Pegylated Paramagnetic Lipid Vesicles
To design and evaluate a Magnetic Resonance Imaging (MRI) contrast agent for tumor detection based on a paramagnetic agent entrapped within non ionic vesicles (niosomes) bearing both polyethylene glyc...
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Charles A. Cuenod,
Alain Luciani,
Jean-Christophe Olivier,
Olivier Clement,
Nathalie Siauve,
Guy Frija
et al.
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S39
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In vivo cellular imaging of magnetically labelled hybridomas in the spleen on a 1.5 T clinical MRI system
Anionic γ-Fe2O3 superparamagnetic nanoparticles have been shown to label efficiently different types of cells because of their negative surface charges. These particles are thus particularly well suit...
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O. Clément,
P. Smirnov,
M. Lewin,
J.C. Bacri,
N. Siauve,
C.A. Cuénod,
F. Gazeau
et al.
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S39-S40
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Improved Paramagnetic Chelate for Molecular Imaging with MRI
Sensitive molecular imaging of sparse biochemical epitopes with magnetic resonance imaging (MRI) requires a targeted contrast agent with enormous paramagnetic influence to overcome partial-volume dilu...
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Patrick M. Winter,
Phillip S. Athey,
Gary E. Kiefer,
Gyongyi Gulyas,
Ralph W. Fuhrhop,
J. David Robertson,
Samuel A. Wickline,
Gregory M. Lanza
et al.
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S40-S41
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An Inexpensive Vascularized Tumor Model for Vascular Imaging
Although many molecular imaging agents, particularly those aimed at imaging intracellular or cellular targets, can be tested in cell cultures, they as well as those agents aimed at the tumor matrix or...
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Max Wu,
Jacqueline Corbeil,
Judith Varner,
David Vera,
Robert Mattrey
et al.
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S41-S42
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Selecting vectors to image apoptosis by phage display technique
One of our current projects is to develop an MRI contrast agent specific for apoptosis by the technique of phage display. One of the potential targets is phosphatidylserine (PS), which is exposed on t...
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Catherine Laumonier,
Jérôme Segers,
Carmen Burtea,
Luce Vander Elst,
Robert. N. Muller
et al.
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S42-S43
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Molecular Imaging of αvβ3-Integrin: An Opportune Biochemical Signature For Oncologic and Cardiovascular Diseases
αvβ3-Integrin is a well-recognized biomarker of angiogenesis expressed on activated endothelial cells. It is a critical element in vascular restenosis where its upregulation by balloon overstretch inj...
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Patrick M. Winter,
Shelton D. Caruthers,
Thomas D. Harris,
Anne H. Schmeider,
Dana Abendschein,
Tillman Cyrus,
Ralph Fuhrhop,
Elizabeth Dietz,
Todd A. Williams,
John S. Allen,
Huiying Zhang,
Samuel A. Wickline,
Gregory M. Lanza
et al.
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S43
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Fold-Carrying Particles: Improvement of Targeted Microbubble Attachment
Targeting of ultrasound contrast materials to the molecules on the vasculature luminal surface may help design selective imaging agents to detect inflammation, vulnerable plaque, apoptosis and angioge...
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A.L. Klibanov,
J.J. Rychak,
S. Kaul,
K. Ley,
J.R. Lindner
et al.
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S43-S44
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Magnetic Resonance: Contrast enhancement of short T2 tissues in the musculoskeletal system
We have implemented an ultrashort TE (UTE) sequence which enables signal to be detected in tissues with very short T2s. We wished to review the effects of contrast administration on tissues with short...
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Graeme M. Bydder
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S44-S45
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Development of Superparamagnetic Particles Dispersions Basic Materials of Markers for Molecular Imaging
Superparamagnetic systems are likely to play a major role in the context of molecular imaging. Their quality control is however difficult. Nuclear Magnetic Relaxation Dispersion (NMRD) profiles of sus...
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R.N. Muller,
A. Ouakssim,
S. Fastrez,
A. Roch,
S. Laurent,
Y. Gossuin,
C. Piérart,
L. Vander Elst
et al.
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S45
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Ferucarbotran-enhanced perfusion MR imaging of the liver in patients with hypervascular hepatocellular carcinomas
The purpose of this study is to determine the utility of ferucarbotran-enhanced perfusion MRI of the liver in the diagnosis of hepatocellular carcinoma (HCC).
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Shinji Hirohashi,
Satoru Kitano,
Toshiaki Taoka,
Nagaaki Marugami,
Kouji Ueda,
Kimihiko Kichikawa
et al.
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S45-S46
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Transition Metal Cluster and Polygadolinium Compounds as a New Paradigm For High Attenuation and/or Relaxivity in Contrast Media Design: Crashing The Molecular r1 = 100 Barrier
We have been developing the supporting chemistry for new types of X-ray and MRI contrast agents by exploiting the unique aspects of high atomic number metal cluster compounds and highly paramagnetic, ...
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Louis Messerle,
Donald Nolting,
Lizann Bolinger,
Alan H. Stolpen,
Brian F. Mullan,
Dale Swenson,
Mark Madsen
et al.
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S46-S47
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Retention of Gadolinium in Human Bone Tissue
This study was undertaken to assess whether gadolinium (Gd) from commercially available MRI contrast agents is retained in human bone tissue following intravenous administration at a routinely used cl...
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W. Gibby,
K. Gibby,
A. Gibby
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S47
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Magnevist ® (gadopentetate dimeglumine) does not interfere with the determination of calcium levels in plasma or serum
Evaluation of the possible influence of Magnevist® (Gd- DTPA, gadopentetate dimeglumine, Schering) on the in vitro measurement of plasma calcium level with the commercially available colorimetric and ...
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Andrea Löwe,
Christian Reh
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S47-S48
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Inhibition of in-Stent Restenosis of Porcine Peripheral Arteries by a Single Intraarterial Injection of Contrast Medium Mixed with Paclitaxel
In a previous study it was demonstrated that intracoronary Paclitaxel dissolved in contrast medium at subtoxic systemic dose levels inhibits in-stent restenosis in porcine coronary arteries. The purpo...
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Thomas Albrecht,
Bruno Scheller,
Claudia Beier,
Alexander Schmitt,
Georg Nickenig,
Ulrich Speck
et al.
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S48
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Virtual MicroCT Angiography with BP20 in Live Mice
MicroCT scanners capable of sub 20-micron spatial resolutions have now been introduced that afford ultrahigh-resolution potential to more effectively monitor in vivo tumor growth and development in li...
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J.P. Weichert,
A.R. Moser,
B.Y. Durkee,
D.E. Bjorling,
M.A. Longino,
F.T. Lee
et al.
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S48-S49
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Contrast ultrasound for sentinel node localization in head and neck cancer
This study was designed to evaluate a minimally invasive contrast-assisted ultrasound technique for sentinel lymph node localization using spontaneously arising canine models of head and neck cancer.
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Erik R. Wisner,
David M. Lurie,
Bernard Seguin,
Frank J. Verstraete
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S49-S50
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Microbubble Kinetics in Indirect Ultrasound Lymphography
We reported on an indirect lymphography method using AF0150 and a method to reproducibly quantify lymph node uptake to help optimize formulations. In this study we aimed to determine the pharmacokinet...
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Yuko Kono,
James Kuo,
Sang-Hee Choi,
Jaqueline Corbeil,
Robert F. Mattrey
et al.
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S50-S51
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Comparison of Macromolecular Contrast Agents for Dynamic Micromagnetic Resonance Lymphangiography
Few methods are currently available to visualize the entire lymphatic system. We recently developed a method of micromagnetic resonance (MR) lymphangiography (MRL) in mice that uses a dendrimer-based ...
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Hisataka Kobayashi,
Satomi Kawamoto,
Robert A. Star,
Peter L. Choyke,
Michael V. Knopp,
Thomas A. Waldmann,
Martine W. Brechbiel
et al.
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S51-S52
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Value Of USPIO (Sinerem®) Enhanced MRI in The Assessment of Axillary Lymph Nodes in Breast Cancer
To assess the diagnostic value of USPIO-enhanced compared to plain MR-imaging (MRI) in the detection of axillary lymph node metastases in patients with breast carcinomas.
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T.H. Helbich,
M. Memarsadeghi,
A. Garlid,
M. Rudas,
A. Kaneider,
W. Matzek,
C.C. Riedl
et al.
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S52
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Iosimenol: The Second Generation of Nonionic Dimers
Unlike the monomeric contrast media (CM), the nonionic dimers iotrolan and iodixanol (ID) are isotonic but also considerably more viscous. Our purpose was to design and develop a low viscosity, high i...
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Milos Sovak,
Ron Terry,
Ondrej Masner,
Claudia Abramjuk,
Bettina Adolph,
Allen Seligson
et al.
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S52-S53
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Immediate reactions to contrast material: first results of the French multicenter study
Immediate reactions to contrast material (CM) are a matter of concern for radiologists. Most of them are due to non specific, toxic mechanisms. However some may be related to IgE-mediated hypersensiti...
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D. Laroche,
P. Dewachter,
C. Mouton-Faivre,
O. Clement,
working goup on contrast agents (CIRTACI)
et al.
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S53-S54
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“This Contrast Medium Will not Burn at All.” Unintended Nocebo Effects and Considerations for the Design of Clinical Trials
Contrast media research often uses subjective measures in patients to assess for improved tolerance of new compounds. Low pain during injection is considered a particular advantage for vascular applic...
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Elvira V. Lang,
Olga Hatsiopoulou,
Timo Koch,
Kevin Berbaum,
Henrietta Logan,
Susan Lutgendorf,
Ted Kaptchuk
et al.
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S54-S55
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Research on Necrosis Avid Contrast Agents: Further Expansion of Scope
Following discoveries of porphyrin and nonporphyrin necrosis-avid contrast agents (NACAs), their great potentialities for myocardial viability determination and therapeutic assessment have been recogn...
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Y. Ni,
D. Huyghe,
F. Chen,
G. Bormans,
A. Verbruggen,
G. Marchal
et al.
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S55
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MRI of Liver Tumors: Comparison of the Iron-Oxide-Based Blood Pool Contrast Medium VSOP-C184 with the Liver-Specific SPIO Resovist and the Low-Molecular Substance Multihance in an Animal Model
VSOP-C184 is an iron-oxide-based superparamagnetic MR contrast medium (SPIO) that can be administered as a bolus. Based on its blood pool properties and strong T1-shortening effect, VSOP-C184 was prim...
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Jörg Schnorr,
Matthias Taupitz,
Susanne Wagner,
Ronny Korn,
Herbert Pilgrimm,
Bernd Hamm
et al.
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S56
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Plasma Volume and Permeability Coefficient measurements in the C6 glioma model using Synchrotron Radiation CT coupled to injection of P743, Xenetix and Iomeron
Brain circulation parameters such as Plasma Volume (PV) and blood brain barrier permeability coefficient (K1) are key issues to improve the understanding of tumor growth process. Synchrotron Radiation...
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G. Le Duc,
I. Troprès,
R. Billet,
S. Bouvier,
A. Joubert,
D. Dallery,
T. Brochard,
C. Nemoz,
R. Santus,
B. Van Der Sanden,
P. Robert,
W.C. Thomlinson
et al.
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S57-S58
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Radiation dose enhancement with an iodinated contrast agent
In medical imaging, the purpose of iodinated contrast agents is to increase the absorption of X rays in blood vessels and soft tissues. The contrast agent circulation in vessels induces a local increa...
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A. Joubert,
J.F. Adam,
H. Elleaume,
M.C. Biston,
A.M. Charvet,
N. Foray,
J.F. Le Bas,
J. Balosso,
F. Estève
et al.
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S58
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Radioiodinated NM404-a Universal Tumor Imaging Agent?
Due to its inability to be metabolized and cleared by membrane associated phospholipases, NM404, a second-generation phospholipid ether (PLE) analog, is undergoing preclinical evaluation as a potentia...
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J.P. Weichert,
A.R. Moser,
S.M. Weber,
C. Qi,
M.A. Longino
et al.
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S58-S59
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The Radiosynthesis of [2-18F] Fluorodeoxyglucose Using a Resin Bound Precursor
To develop solid supported precursors for F-18 radiolabelling to enable fast simple manufacture of F-18 radiopharmaceuticals. This has been demonstrated with FDG.
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D. Bouvet,
G. Brown,
R. Brown,
S.M. Champion,
A. Devenish,
A.M.R. Gibson,
Y. Hu,
A. Jackson,
I. Khan,
N. Ma,
N. Millot,
H. Wadsworth,
F. Brady,
S.K. Luthra
et al.
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S59-S60
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Assessment of Therapy in Hypertrophied Hearts Using Contrast Enhanced MRI
The mitochondrial and sarcolemmal potassium-channel opener and vasodilator nicorandil preserves viability, microvascular integrity and improves function in nonhypertrophied ischemic hearts. However, t...
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Maythem Saeed,
Simon Schalla,
Wolfgang Ebert,
Mitsuaki Chujo,
Charles B. Higgins
et al.
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S60
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All-in-one imaging protocols for potential living liver donors: comparison of MRT and Multislice-CT with intraoperative findings
To compare all-in-one Multidetector-CT- with MRI for evaluation of potential living liver donors.
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Stefan G. Ruehm,
Tobias Schroeder,
Max Malagó,
Silvio Nadalin,
Jörg F. Debatin
et al.
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S61
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MR-Angiography of the Coronary Arteries with the New Iron Oxide Blood-Pool Contrast Medium VSOP-C184: Results of a Phase Ib Clinical Trial
VSOP-C184 is a monomer coated very small iron oxide blood-pool contrast medium. The substance is bolus-applicable and proved to be well-tolerated in a phase I clinical trial. In a group of six volunte...
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Matthias Taupitz,
Jörg Schnorr,
Marc Dewey,
Susanne Wagner,
Lasse Krug,
Herbert Pilgrimm,
Irina Kravec,
Bernd Hamm
et al.
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S61-S62
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A Novel Double-Contrast Technique to Facilitate MRI-Guided Vascular Interventions: Combined Use of a Blood-Pool Agent and Carbon Dioxide
An accurate visualization of vessels and catheter-tip is essential during MRI-guided vascular interventions. Because nefrotoxicity of large quantities of Gadolinium-contrast agents, alternatives are n...
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Robbert M. Maes,
Frank K. Wacker,
Jack A. Jesberger,
Jeffrey L. Duerk,
Jonathan S. Lewin
et al.
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S62-S63
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Thromboembolic disease: Assessment with whole body MR venography
To assess the diagnostic accuracy of a comprehensive MR protocol comprising MR angiography of the pulmonary arteries and whole body MR venography for the detection of thromboembolic diesease.
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Stefan G. Ruehm,
Knut Kroeger,
Silke Bosk,
Sandra Massing,
Serban Mteiescu,
Jörg F. Debatin
et al.
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S63
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MR Imaging-Guided Endovascular Procedures: Are Contrast Agents Necessary to Improve Passive Tracking Techniques?
The purpose of this study is to compare the feasibility of passive catheter tracking in various anatomic locations using a bright blood MR sequence with and without the use of an intravascular contras...
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Frank K. Wacker,
Claudia M. Hillenbrand,
Jeffrey L. Duerk,
Jonathan S. Lewin
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S63-S64
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Comparative Clinical Pharmacokinetic Studies with Levovist and SonoVue
Functional microbubble studies have been developed with the air bubble Levovist but newer perfluoro-based agents such as SonoVue are increasingly used because of their non-linear responses at low acou...
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Adrian Lim,
Nayna Patel,
Rob Eckersley,
Simon Taylor-Robinson,
David Cosgrove,
Martin Blomley
et al.
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S64-S65
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Assessment of Brain Perfusion in Stroke Patients with Echo Contrast Enhanced Transcranial Ultrasound: Preliminary Results
Intravenous ultrasound contrast imaging has been evaluated over the past several years for transcranial vascular imaging. Otherswe have shown that ultrasound contrast enables the sonographer to assess...
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Thilo Hoelscher,
Lama Alkhoury,
Yu D. Cheng,
Scott Olson,
Pat Von Behren,
Robert F. Mattrey,
Pat Lyden
et al.
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S65-S66
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Focal liver lesion characterization using low acoustic power ultrasound imaging
To determine if real-time low acoustic power imaging with SonoVue (Bracco, Italy), a sulphur hexafluoride based microbubble contrast agent, increases diagnostic performance of baseline ultrasound (US)...
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Emilio Quaia,
Elisa Mosconi,
Francesca Degobbis,
Roberto Pozzi Mucelli
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S66
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Use Of Contrast-Enhanced Ultrasonography To Monitor Local Ablative Treatment Of Liver Cancer
While surgery remains the treatment of choice for patients meeting criteria for resection, minimally invasive treatments (MITs) are expanding, as the majority of liver cancer patients have advanced di...
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Alberto Spinazzi,
Marc Engelhardt
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S66-S67
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Characterisation and Design of Microbubble Ultrasound Contrast Agents
The benefits of microbubble ultrasound contrast agents have been repeatedly demonstrated, both in ultrasound image enhancement and more recently in drug and gene delivery applications. However, existi...
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Eleanor Stride,
Nader Saffari,
Peter Dawson
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S67-S68
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Validation of Ultrasound Contrast Destruction Imaging for Flow Quantification
To validate In vitroa kinetic flow model based on microbubble signal decay curve obtained during ultrasound emission.
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Olivier Lucidarme,
Yuko Kono,
Jacqueline Corbeil,
Sang-Hee Choi,
Robert F. Mattrey
et al.
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S68
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Non-invasive quantitative assessment of angiogenesis with contrast enhanced functional ultrasound imaging in a non-tumor animal model
Angiogenesis is a complex process and while tumors are an ideal model to study angiogenesis, their growth is influenced by many local and systemic factors that introduce variability within the same an...
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Olivier Lucidarme,
Yuko Kono,
Jacqueline Corbeil,
Sang-Hee Choi,
Robert F. Mattrey
et al.
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S68-S69
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Structural and Functional Characterization of Chronic Obstructive Lung Disease and Emphysema Using 3He- MRI: Comparison with CT and Pulmonary Function Tests
Besides the selective visualization of ventilated airspaces 3He-MRI provides additional structural and functional information about airways and airspaces. Preliminary experience suggests that 3He-MRI ...
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Hans-Ulrich Kauczor,
Sebastian Ley,
Klaus Gast,
Alexander Biedermann,
Julia Zaporozhan,
Claus-Peter Heussel,
Wolfgang Schreiber
et al.
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S69-S70
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Dynamic Interventional MR Imaging Using Hyperpolarized C-13
The para-hydrogen method has been used to polarize the 13C atoms in selected water-soluble molecules. The degree of polarization, achieved by recently developed methods, is in the order of 35% which i...
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K. Golman,
L.E. Olsson,
J.S. Petersson,
J.H. Ardenkjaer-Larsen,
O. Axelsson
et al.
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S70-S71
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Fluorinated Substances as Contrast Agents for Lung Imaging Using 19F-MRI
Direct MRI of gas filled lung remains difficult due to low spin density of gas and strong susceptibility differences between tissue and gas spaces. The most successful technique to compensate for the ...
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C.P. Heussel,
A. Scholz,
U. Wolf,
S. Ley,
K. Gast,
K. Markstaller,
B. Eberle,
N. Weiler,
M. Quintel,
M. Fabel-Schulte,
W.G. Schreiber,
H.-U. Kauczor,
M. Thelen
et al.
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S71-S72
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Optical imaging and Quantitation
Optical imaging of biological tissue commenced with Continuous Wave (CW) approaches that measured the optical attenuation. However, this provided limited information since the attenuation is dependent...
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David J. Hall,
Guobin Ma,
Frederic Lesage,
Pascal Gallant
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S72-S73
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Toward the Goal of Signal Quantification in Contrast-Enhanced Optical Imaging
Contrast enhanced diagnostic imaging using incident laser-generated light photons to interrogate living tissues is a relatively new but intensively pursued field. Most investigators have focused their...
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Robert Brasch,
Laure Fournier-Dujardin,
Vincenzo Lucidi,
Kirill Berejnoi,
Yanjun Fu,
Jonathan Palley,
Stavros Demos
et al.
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S73-S74
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A Receptor-Binding Optical Agent for In Vivo Measurement of Receptor Biochemistry
Our objective was to demonstrate receptor-binding properties of an optically labeled receptor-binding agent, Cy5.5-DTPA-galactosyl-dextran.
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David Vera,
Robert Mattrey,
Carl Hoh,
Laura McIntosh
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S74-S75
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Real-Time Tumor Labeling and Biodistribution Imaging Using Folate-Receptor (FR) Targeted Imaging Agents
We are developing agents for the real-time guidance of surgical procedures directed at tumors, in this case ovarian cancer. Folate receptor (FR) is overexpressed in certain cancers, particularly ovari...
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David A. Benaron,
Ilian H. Prachikov,
Peter G. Maxim,
Jeffrey L. Carson,
Phillip S. Low
et al.
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S75
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