Rationale and Objectives
The objective of this study was to demonstrate that an intra-arterial liver therapy
clinical research database system is a more workflow efficient and robust tool for
clinical research than a spreadsheet storage system. The database system could be
used to generate clinical research study populations easily with custom search and
retrieval criteria.
Materials and Methods
A questionnaire was designed and distributed to 21 board-certified radiologists to
assess current data storage problems and clinician reception to a database management
system. Based on the questionnaire findings, a customized database and user interface
system were created to perform automatic calculations of clinical scores including
staging systems such as the Child-Pugh and Barcelona Clinic Liver Cancer, and facilitates
data input and output.
Results
Questionnaire participants were favorable to a database system. The interface retrieved
study-relevant data accurately and effectively. The database effectively produced
easy-to-read study-specific patient populations with custom-defined inclusion/exclusion
criteria.
Conclusions
The database management system is workflow efficient and robust in retrieving, storing,
and analyzing data.
Key Words
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References
- A comprehensive clinical research database based on CDISC ODM and i2b2.Stud Health Technol Inform. 2014; 205: 1115-1119
- MySQL database and PHPMyAdmin installation. PHP and MySQL manual.Springer, London2004: 461-473
- Manage data for free with MySQL. Book manage data for free with MySQL.(City: Element K Journals)2001: 7-10
- Database systems: design, implementation, and management.9 ed. Cengage Learning, Boston, Massachusetts2009
- Design and endpoints of clinical trials in hepatocellular carcinoma.J Natl Cancer Inst. 2008; 100: 698-711
- Use of electronic medical records in oncology outcomes research.Clinicoecono Outcomes Res. 2010; 2: 1-14
- Practical applications of usability theory to electronic data collection for clinical trials.Contemp Clin Trials. 2005; 26: 376-385
- Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support.J Biomed Inform. 2009; 42: 377-381
- MySQL database provides full transactional support.Worldwide Databases. 2002; 14 (0-N/A)
Oracle Improves Database Performance with Latest Development Milestone Release for MySQL 5.7; New Release of the World's Most Popular Open Source Database is 2x Faster than MySQL 5.6 and Over 3x Faster than MySQL 5.5 in Benchmark Tests. Book Oracle Improves Database Performance with Latest Development Milestone Release for MySQL 5.7; New Release of the World's Most Popular Open Source Database is 2x Faster than MySQL 5.6 and Over 3x Faster than MySQL 5.5 in Benchmark Tests. City 2014.
- Building an integrated neurodegenerative disease database at an academic health center.Alzheimers Dement. 2011; 7: e84-93
- Automatic MySQL database performance tuning.in: Parkes D. Lowman M. Andres C. Pro python system administration. Apress, 2010: 329-348
- microPIR: an integrated database of microRNA target sites within human promoter sequences.PloS One. 2012; 7: e33888
Article info
Publication history
Published online: January 29, 2015
Accepted:
December 6,
2014
Received:
July 30,
2014
Footnotes
Funding Sources: Funding and support for this study has been provided by National Institutes of Health/National Cancer Institute R01 CA160771, P30 CA006973, and Philips Research North America, Briarcliff Manor, NY.
Identification
Copyright
© 2015 AUR. Published by Elsevier Inc. All rights reserved.
