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Overdiagnosis Detrimental, Resection Consequential, NLST Challengeable

Published:October 22, 2015DOI:https://doi.org/10.1016/j.acra.2015.07.013
      We differ in some respects with the views expressed by Dr. Mortani Barbosa Jr. regarding the level of overdiagnosis and the consequences of resection mandated by screen-identified lung cancer (
      • Mortani Barbosa Jr, E.J.
      Lung cancer screening overdiagnosis: reports of overdiagnosis in screening for lung cancer are grossly exaggerated.
      ). Additionally, reflecting concerns about the design limitations of the National Lung Screening Trial (NLST), we think its positive outcome is challengeable.
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