Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report

Published:April 13, 2020DOI:https://doi.org/10.1016/j.acra.2020.04.002
      Since the initial reports of the novel coronavirus disease (COVID-19) in December 2019 in Wuhan, China, and the declaration by the World Health Organization of the disease as a pandemic, increasing numbers of patients are diagnosed with COVID-19 globally on a daily basis. While initially fever, cough and dyspnea were thought to be the dominant symptoms, other unusual presentations of COVID-19 such as altered olfactory function have been increasingly recognized. Recently, isolated anosmia/hyposmia is reported as a marker of COVID-19. The onset of anosmia was sudden in majority of the cases and most had a concomitant decrease in taste sensation (
      • Brann D.
      • Tsukahara T.
      • Weinreb C.
      • et al.
      Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients.
      ).
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