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T2-Weighted Image Radiomics Nomogram to Predict Pancreatic Serous and Mucinous Cystic Neoplasms

Published:November 12, 2022DOI:https://doi.org/10.1016/j.acra.2022.10.008
      With the advent of cross-sectional imaging, incidental pancreatic cystic neoplasms have become increasingly detectable. Serous cystic neoplasms (SCNs) and mucinous cystic neoplasms (MCNs) are two common types of pancreatic cystic neoplasms (
      • van Huijgevoort NCM
      • Del Chiaro M
      • Wolfgang CL
      • et al.
      Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines.
      ). SCN is a benign neoplasm that does not require surgical treatment unless symptoms related to the compression of adjacent organs are present (
      European study group on cystic tumors of the P. European evidence-based guidelines on pancreatic cystic neoplasms.
      ). MCN is a precancerous lesion; therefore, surgical resection is generally recommended (
      European study group on cystic tumors of the P. European evidence-based guidelines on pancreatic cystic neoplasms.
      ,
      • Tanaka M
      • Fernandez-Del Castillo C
      • Kamisawa T
      • Jang JY
      • Levy P
      • Ohtsuka T
      • Salvia R
      • Shimizu Y
      • Tada M
      • Wolfgang CL
      Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
      ). Using conventional imaging parameters, it is difficult to differentiate SCN from MCN, especially when both are unilocular (
      • Mamone G
      • Barresi L
      • Tropea A
      • et al.
      MRI of mucinous pancreatic cystic lesions: a new updated morphological approach for the differential diagnosis.
      ).

      Key Words

      Abbreviations:

      ADC (apparent diffusion coefficient), AIC (Akaike information criterion), AUC (area under the curve), BMI (body mass index), CI (confidence interval), CT (computed tomography), DCA (decision curve analysis), DWI (diffusion-weighted imaging), FOV (field of view), ICC (intraclass correlation coefficient), LASSO (least absolute shrinkage and selection operator), MCN (mucinous cystic neoplasms), MPD (main pancreatic duct), MRI (magnetic resonance imaging), NPV (negative predictive value), OR (odds ratio), PPV (positive predictive value), rad-scores (radiomics scores), ROI (regions of interest), SCN (serous cystic neoplasms), TE (time of echo), TR (time of repetition), T1WI (T1 weighted imaging), T2WI (T2 weighted imaging), VOI (volume of interest)
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