Rationale and objectives
The recently developed ultrasound based tools using attenuation coefficient (AC) and
scatter distribution coefficient (SDC) values can be used to quantify hepatic fat
content in patients with non-alcoholic fatty liver disease (NAFLD). However, currently
the impact of respiratory phase on these measurements is not known. The purpose of
this study is to compare AC and SDC measurements acquired at peak inspiration and
end expiration phases.
Materials and methods
AC and SDC measurements were obtained in 50 patients with NAFLD. Tissue Attenuation
Imaging (TAI) and Tissue Scatter Distribution Imaging (TSI) tools were utilized to
measure AC and SDC values, respectively. Five measurements were performed at respiratory
phases using TAI and TSI tools and the median values were noted. Subgroup analyses
were performed and Wilcoxon signed rank test was used for comparison of the measurements.
Results
The median values of the AC measurements at peak inspiration and end expiration phases
were 0.87 dB/cm/MHz and 0.89 dB/cm/MHz, respectively. The median values of the SDC
measurements at peak inspiration and end expiration phases were 97.91 and 96.62, respectively.
There were no statistically significant differences in AC and SDC measurements between
the respiratory phases except for AC measurements in BMI <30 kg/m2 subgroup.
Conclusion
Our results revealed that respiratory phases have no impact on SDC measurements. However,
while the AC measurements in BMI ≥30 kg/m2 subgroup showed no significant difference, there was a significant difference in
AC measurements in BMI <30 kg/m2 subgroup between the respiratory phases.
Key Words
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Article info
Publication history
Published online: January 09, 2023
Accepted:
December 13,
2022
Received in revised form:
December 10,
2022
Received:
November 7,
2022
Publication stage
In Press Corrected ProofFootnotes
Note: The results of this study were presented with preliminary analyses as an oral presentation at EUROSON SCHOOL 2022 Congress which was organized at Istanbul/Turkey on October 1-2, 2022.
Identification
Copyright
© 2022 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.
