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Fat Has an Endocrine Function

Published:December 28, 2022DOI:https://doi.org/10.1016/j.acra.2022.12.022
      Although catheter coronary angiography has been the standard imaging examination for evaluating coronary artery disease for many years, it is an invasive and expensive procedure. Due to its lower cost and noninvasive nature, coronary computed tomographic angiography (CCTA) has become the primary diagnostic test for patients with chest pain. Another advantage of CCTA is that adjacent fat is also imaged. Adipose tissue serves not only to store excess calories, but fat also has an endocrine function, secreting adipokines which participate in the regulation of metabolism. While insufficient adipose tissue can be detrimental, excess adipose tissue contributes to the development of type II diabetes mellitus, cardiovascular disease and several types of cancers (
      • Kim SG
      Quantitative imaging of body fat distribution in the era of deep learning.
      ).
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