Since described nearly 20 years ago (
1
), 4D parathyroid CT has become widely adopted for preoperative localization of parathyroid
adenoma in the setting of biochemically diagnosed primary hyperparathyroidism. The
variable appearances and typical locations of parathyroid adenomas along the embryologic
tracts of descent have been well described (
2
). Parathyroid adenomas are typically distinguishable from lymph nodes due to distinctive
enhancement patterns (
2
). In this issue of Academic Radiology, Paul Bunch et al. (
3
) investigate whether we should be prospectively looking for and reporting possible
parathyroid adenomas on the routine neck and chest CT examinations.To read this article in full you will need to make a payment
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REFERENCES
- Improved preoperative planning for directed parathyroidectomy with 4-dimensional computed tomography.Surgery. 2006; 140 (discussion 940-941): 932-940https://doi.org/10.1016/j.surg.2006.07.028
- Parathyroid 4D CT: what the surgeon wants to know.Radiographics. 2020; 40: 1383-1394https://doi.org/10.1148/rg.2020190190
- Opportunistic parathyroid gland assessment on routine CT Could Decrease Morbidity from Undiagnosed Primary Hyperparathyroidism.Acad Radiol. 2022; S1076-6332: 00317-00318https://doi.org/10.1016/j.acra.2022.05.014
- Increased mortality and morbidity in mild primary hyperparathyroid patients. The Parathyroid Epidemiology and Audit Research Study (PEARS).Clin Endocrinol (Oxf). 2010; 73: 30-34https://doi.org/10.1111/j.1365-2265.2009.03766.x
- Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus.Osteoporos Int. 2017; 28: 1-19https://doi.org/10.1007/s00198-016-3716-2
- The American Association of Endocrine Surgeons Guidelines for definitive management of primary hyperparathyroidism.JAMA Surg. 2016; 151: 959-968https://doi.org/10.1001/jamasurg.2016.2310
- Failure to diagnose hyperparathyroidism in 10,432 patients with hypercalcemia: opportunities for system-level intervention to increase surgical referrals and cure.Ann Surg. 2017; 266: 632-640https://doi.org/10.1097/SLA.0000000000002370
- Incidence and prevalence of primary hyperparathyroidism in a racially mixed population.J Clin Endocrinol Metab. 2013; 98: 1122-1129https://doi.org/10.1210/jc.2012-4022
- Enlarged parathyroid glands on trauma computed tomography: frequency and assessment for possible primary hyperparathyroidism.J Comput Assist Tomogr. 2021; 45: 926-931https://doi.org/10.1097/RCT.0000000000001214
Article info
Publication history
Published online: March 18, 2023
Accepted:
February 20,
2023
Received:
February 20,
2023
Publication stage
In Press Corrected ProofFootnotes
Disclosures: Dr. Guenette is supported by the Association of University Radiologists with a GE Radiology Research Academic Fellowship.
Identification
Copyright
© 2023 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.
